Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons
Vaysset H*, Meers C¨, Cury J, Bernheim A*, Sternberg S*
Nature Microbiology, doi.org/10.1038/s41564-024-01889-2 (2024)

A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway
Bonhomme D*, Vaysset H*, Ednacot E., Rodrigues V., Cury J., Hernandez Trejo V., Benaroch P., Morehouse B, Bernheim A.*, Poirier E.*
bioRxiv 10.1101/2024.09.18.613514

A family of lanthipeptides with anti-phage function
Shomar H., Tesson F., Guillaume M., Ongenae V., Le Bot ., Georjon H., Mordret E., Zhang L., van Wezel G., Rozen D., Briegel A., Zirah S., Claessen D., Li Y., Bernheim A.
bioRxiv, 10.1101/2024.06.26.600839 (2024)

Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information
Gaborieau B*, Vaysset H*., Tesson H*., Charachon I., Dib N., Bernier J., Dequidt T., Georjon H., Clermont O., Hersen P., Debarbieux L, Ricard JD, Denamur E., Bernheim A
Nature Microbiology, 10.1038/s41564-024-01832-5 (2024)

Conservation of antiviral systems across domains of life reveals immune genes in humans
Cury J.*, Haudiquet M.*, Hernandez-Trejo V., Mordret E*., Hanouna A., Rotival M, Tesson F.,Bonhmme, D. Ofir G., Quintana-Murci L., Benaroch P., Poirier Z. P*., Bernheim A.*
Cell Host and Microbes, 10.1016/j.chom.2024.08.002 (2024)
Scientific Commentary: Cell Host and Microbes

Viperin immunity evolved across the tree of life through serial innovations on a conserved scaffold
Shomar H*.,Georjon H.*, Feng Y, Olympio B, Cury J, Tesson F., Wu F*., Bernheim A*.
Nature Ecology and Evolution, 10.1038/s41559-024-02463-z, https://hal.science/hal-04690206 (2024)
Scientific Commentary: Nature Research Briefing

Exploring the diversity of anti-defense systems across prokaryotes, phages, and mobile
genetic elements
Tesson F.*, Huiting E.*, Wei L, Ren J., Johnson M., Planel R., Cury J., Feng Y., Bondy-Denomy J*, Bernheim A.*
Nucleic Acids Research, 10.1093/nar/gkae1171 (2024)

A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.
Tesson F., Planel R., Egorov A., Georjon H., Vaysset H., Brancotte B., Neron B., Mordret E., Atkinson G., Bernheim A*, Cury J*
Peer Community Journal, 10.1101/2024.01.25.577194 (2024)

The immune modules conserved across the tree of life: Towards a definition of ancestral immunity
Bernheim A.*, Cury J, Poirier Z. E*.
Plos Biology, 10.1371/journal.pbio.3002717 (2024) (Essay)

A virally-encoded tRNA neutralizes the PARIS antiviral defence system
Burman N.*, Belukhina S.* , Depardieu F.*, Wilkinson R.*, Skutel M., Santiago-Frangos A., Graham A., Livenskyi A., Chechenina A., Morozova N, Zahl T., Henriques W., Buyukyoruk M., Rouillon C., Shyrokova L, Kurata, T Hauryliuk V, Severinov K, Groseille J, Thierry A, Koszul R., Tesson F., Bernheim A, Bikard D., Wiedenheft B, Isaev A.
Nature, 0.1038/s41586-024-07874-3 (2024)

Strain phylogroup and environmental constraints shape Escherichia coli dynamics and diversity over a twenty-year human gut time series
Condamine B, Morel-Journel T., Tesson F., Magnan M., Bernheim A., Denamur E., Blanquart F. , Clermont O.
ISME Journal, 10.1093/ismejo/wrae245 (2024)

The highly diverse antiphage defence systems of bacteria
Georjon H, Bernheim A.
Nature Reviews Microbiology, 1/-15 (2023) (Review)
Chosen for Nature Reviews Microbiology 20th Anniversary collection.

Genomic characterization of the antiviral arsenal of Actinobacteria
Georjon H., Tesson F., Shomar H*., Bernheim A*.
Microbiology Aug;169(8):001374 (2023)

Synergy and regulation of antiphage systems: toward the existence of a bacterial immune system?
Tesson F., Bernheim A.
Curr Opinion in Microbiology Feb:71:102238 (2023) (Review)

Immunité bactérienne: à la découverte d’un nouveau monde
A Hardy, H Shomar, A Bernheim
médecine/sciences 39 (11), 862-868 (2023) (Review)

Systematic and quantitative view of the anti-viral arsenal of prokaryotes
Tesson F., Hervé A., Touchon M., Mordret E., d’Humières C., Cury J., Bernheim A.
Nature Communications, 13:256 (2022)
Scientific Commentary: Nature Reviews Microbiology

CRISPR-Cas and restriction-modification team up to achieve long-term immunity
Cury J, Bernheim A
Trends in Microbiology, S0966-842X(22)00091-9. (2022) (Comment)

An expanding arsenal of immune systems that protect bacteria from phages
Millman A., Melamed S., Leavitt A., Doron S., Bernheim A, Hör J., Lopatina A., Ofir G., Hochhauser D., Stokar-Avihail A., Tal N., Sharir S., Voichek M., Erez Z., Lorenzo M Ferrer J., Dar D., Kacen A., Amitai G., Sorek R.
Cell Host and Microbes, 30,1556-1569 (2022)

Phages and their satellites encode hotspots of antiviral systems
Rousset F., Depardieu F., Miele S., Dowding J., Liebermann E., Garry D., Rocha E.P.C, Bernheim A, Bikard D.
Cell Host and Microbes, S1931-3128(22)00104-4(2022)

Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons
Klompe S, Jaber N, Bel L, Mohabir J,  Bernheim A, Sternberg S.
Molecular Cell 82 (3), 616-628e5 (2022)